Intestinal Radioprotection by Vitamin E (Alpha-Tocopherol)
نویسندگان
چکیده
منابع مشابه
Determination of serum alpha-tocopherol (vitamin E) by high-performance liquid chromatography.
We report a fast, simple high-performance liquid-chromatographic assay for serum alpha-tocopherol, with use of a reversed-phase column and tocol as internal standard. Only 200 microliter of serum is required. Isocratic elution of the n-hexane extract is done within 6 min; total analysis time is less than 1 h. Within-day precision (CV) was 2.3% for 24 samples of a normal plasma pool (mean concn,...
متن کاملFree radical interaction between vitamin E (alpha-, beta-, gamma- and delta-tocopherol), ascorbate and flavonoids.
Despite a large number of previous studies, the mechanism of free radical interaction between vitamin E (VE) (alpha-, beta-, gamma- and delta-tocopherol) and ascorbate or flavonoids as coantioxidants remains unclear. VE, particularly alpha-tocopherol, shows less antioxidant activity against peroxyl radicals, suggesting that VE possesses functions that are independent of its antioxidant/radical-...
متن کاملThe molecular basis of vitamin E retention: structure of human alpha-tocopherol transfer protein.
Alpha-tocopherol transfer protein (alpha-TTP) is a liver protein responsible for the selective retention of alpha-tocopherol from dietary vitamin E, which is a mixture of alpha, beta, gamma, and delta-tocopherols and the corresponding tocotrienols. The alpha-TTP-mediated transfer of alpha-tocopherol into nascent VLDL is the major determinant of plasma alpha-tocopherol levels in humans. Mutation...
متن کاملEffect of DL-alpha-tocopherol (vitamin E) on the differentiation of mouse myeloid leukemia cell.
The effect of DL-alpha-tocopherol on the differentiation of the mouse myeloid leukemia cell line (M1) was investigated using fluorometry. The reliability of the fluorometric determination was verified by the mutual overlapping of the curves of disappearance of the radioactivity recovered as alpha-tocopherol and the loss of its fluorescence. alpha-Tocopherol solubilized into the culture medium w...
متن کاملSimultaneous determination of homologues of vitamin E and coenzyme Q and products of alpha-tocopherol oxidation.
A sensitive procedure is described for the simultaneous determination of vitamin E and coenzyme Q homologues and alpha-tocopherol oxidation products using two-isocratic step high pressure liquid chromatography (HPLC) and electrochemical detection in the oxidative mode. Zinc-catalyzed reduction in a post-column reactor allows the detection of alpha-tocopherolquinone, epoxy-tocopherolquinone, and...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Annals of Surgery
سال: 1995
ISSN: 0003-4932
DOI: 10.1097/00000658-199522240-00008